Endocrine Abstracts

Objective and importance: Among pathologies associated with acromegaly, have great importance both colon benignant neoformations such polyposis, and cardiovascular complications such as miocardic hypertrophy, arterial hypertension, coronaropathy and valvulopathy.Clinical presentation: We report a case of 74-years-old woman with acromegaly, diabetes mellitus type II and hyperthyroidism, who was admitted at our clinic with symptoms of chronic febricula wit...

Objective: Acromegaly is a rare pituitary disease due to excessive secretion of GH. Insulin resistance, impaired glucose tolerance (IGT) and diabetes mellitus (DM) are common features in acromegaly. Seventy-four active acromegalic patients were retrospectively evaluated in order to determine the impact of family history for diabetes mellitus on glucose tolerance, insulin resistance and beta-cell function.Patients and methods: We studied 74 patients with ...

Introduction: Insulin resistance is a common finding in women with polycystic ovary syndrome (PCOS) and is considered a major aspect in this condition, as it likely plays a role in the pathogenesis of both hyperandrogenism and several metabolic abnormalities, frequently found in these women. Despite its significance, prevalence of insulin resistance in PCOS subjects is still unclear, as it was assessed in small samples and/or by using surrogate parameters of insulin action. Mo...